Applications and Experience with PCR-Based Assays to Predict Blood Group Antigens

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Applications and Experience with PCR-Based Assays to Predict Blood Group Antigens.

DNA-based tests are increasingly being used to predict a blood group phenotype. This is possible because genes encoding 29 of the 30 blood group systems have been cloned and sequenced, and the molecular bases associated with most antigens have been determined. RBCs carrying a particular antigen, if introduced into the circulation of an individual who lacks that antigen, can elicit an immune res...

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ABO blood group antigens in patients with psoriasis and pemphigus vulgaris

Background: The ABO blood group antigens play a role in thepathophysiology of some diseases and several researches haveinvestigated this relationship in the field of dermatology. In thepresent study, an attempt was made to find the distribution ofblood types in patients with pemphigus vulgaris and chronicplaque type psoriasis.Method: Fifty patients with chronic plaque type psoriasis, 50patients...

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Relationship of blood groups to pemphigus: Do blood group antigens have a biological role? A Case-control study

Background: ABO blood group antigens may play a role in the pathophysiology of certain diseases. Several studies have investigated the relation between blood group and autoimmune disorders. In this research, we evaluated the associations between ABO blood types and rhesus (Rh) factor in pemphigus patients.Methods: In this case-control, hospital-based study, we evaluated the prevalence of blood ...

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Rh and LW blood group antigens

History and nomenclature The Rh system is second only to the ABO system in importance in transfusion medicine because Rh antigens, especially D, are highly immunogenic and cause hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions (HTRs). HDFN was first described by a French midwife in 1609 in a set of twins, one of whom was hydropic and stillborn, whereas the o...

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ژورنال

عنوان ژورنال: Transfusion Medicine and Hemotherapy

سال: 2009

ISSN: 1660-3818,1660-3796

DOI: 10.1159/000212062